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KMID : 0380620130450020235
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Korean Journal of Food Science and Technology
2013 Volume.45 No. 2 p.235 ~ p.240
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Analysis and Risk Assessment of Aflatoxin M1 in Infant Formula
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Kang Young-Woon
Song Jeong-Eon
Seo Jung-Heok
Park Sung-Kug
Kim Mee-Hye
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Abstract
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To analyze aflatoxin M1 (AFM1), we dissolved infant formula in warm water and cleaned it by using an immunoaffinity column (IAC). The amount of AFM1 was determined by high-performance liquid chromatography coupled with fluorescence detection. AFM1 was detected in 281 of 439 samples. Thus, the detection rate of AFM1 was 64.0%. The average concentration of AFM1 in positive samples was 2.6 ng/kg (of prepared formula). The estimated daily intake (EDI) of AFM1 through infant formula was 0.087-0.646 ng/kg body weight/day and the additional number of cases of liver cancer associated with exposure to AFM1 would be 0.003-0.020 cancer cases/1,000,000. Because there is less than 1 cancer case/ 1,000,000 per year, the exposure to AFM1 through infant formula in Korea is considered to be an unlikely human health concern.
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KEYWORD
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aflatoxin M1, risk assessment, contamination, infant formula
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